BIOLOGICAL ROLES AND THERAPEUTIC POTENTIAL OF G PROTEIN-COUPLED RECEPTORS FOR FREE FATTY ACIDS AND METABOLIC INTERMEDIATES

Biological roles and therapeutic potential of G protein-coupled receptors for free fatty acids and metabolic intermediates

Several G protein-coupled receptors that transmit signals in response to dietary Topicals free fatty acids (FFAs) as well as endogenous metabolites, such as lactate and 3-hydroxybutyrate, have been discovered.These receptors are shown to sense levels of energy substrates or metabolic states of the body, and regulate metabolism and endocrine functio

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Interaction with a phage gene underlie costs of a β-lactamase

ABSTRACT Wooden Train Set The fitness cost of an antibiotic resistance gene (ARG) can differ across host strains, creating refuges that allow the maintenance of an ARG in the absence of direct selection for its resistance phenotype.Despite the importance of such ARG-host interactions for predicting ARG dynamics, the basis of ARG fitness costs and t

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